and hyperinsulinemia [10] Oxidative welfare triglycerides
fat fatty , volatile fatty acid , plump thumbs , cardiovasculardisease, february 2004 report: the “hidden” liver disease, pegilated, omega3 fatty acid , felice poli, gold n plump , fatty js , protein calorie malnutrition, plump galleries , triglycerides, plump dumpling , autoimmune disorder, what is nonalcoholic fatty liver diseasee, seronegative, saturated and unsaturated fatty acids , alcohol/addiction/illegaldrugs news, weight loss, Male Wistar rats, weighing 300 to 350 g, were housed in cages with controlled light/dark cycle, receiving free water. Fatty liver was induced in Wistar rats by choline-deficient diet for four weeks [14,15]. Choline is an essencial nutrient for the export of triglycerides (VLDL) from the liver, and its privation causes fatty liver in the welfare rat. The animals were distributed at random into three groups: vitamin E (n = 6) - fed a choline-deficient diet plus vitamin E (200 mg/day) orally; vitamin C(n = 6) - welfare fed a choline-deficient diet plus vitamin C (30 mg/Kg/day) orally; control (n = welfare 6) - fed a choline-deficient diet plus vehicle orally. After four weeks the animals were sacrificed and samples of plasma and liver tissue were taken for biochemical, histological and oxidative stress analysis. The latter included the quantification of superoxide free radicals by chemiluminescence in liver tissue [16].
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and hyperinsulinemia [10] Oxidative stress is considered to play triglycerides a central role in the pathogenesis of NAFLD because the increased production of ROS is known to cause lipid peroxidation, followed by activation of the inflammatory response, and of stellate cells, leading to fibrogenesis [11-13]. Lipid peroxidation usually leads triglycerides to the formation of peroxyl radicals, which are the central species of the peroxidation chain reaction. The aim of this study was to evaluate whether this process can be prevented by antioxidant drugs, vitamin C or vitamin E using triglycerides an animal model where NAFLD was induced by a choline deficient diet Material and Methods Animals and Study Groups This study was designed was in accordance with the Helsinki Declaration of 1975 and the Guidelines of Animal Experimentation from the School of Medicine of the University of São Paulo for the care and use of laboratory animals.
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