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| fat fatty , volatile fatty acid , plump thumbs , cardiovasculardisease, february 2004 report: the “hidden” liver disease, pegilated, omega3 fatty acid , felice poli, gold n plump , fatty js , protein calorie malnutrition, plump galleries , triglycerides, plump dumpling , autoimmune disorder, what is nonalcoholic fatty liver diseasee, seronegative, saturated and unsaturated fatty acids , alcohol/addiction/illegaldrugs news, weight loss, | Eligibility Ages Eligible for Study: 18 Years - 45 Years, Genders Eligible for Study: Both Criteria Inclusion Criteria: All 18 – 45 years old Study 1 Class I obesity (weighing less than 300 lbs). Abnormal liver biochemistries and scheduled for liver biopsy as part of clinical evaluation. Study 2 fat girls com Class II and III obese patients scheduled to undergo gastric bypass fat girls com surgery. Exclusion Criteria: Active or previous infection with hepatitis B or C, as well as other liver disease. History of alcohol abuse Diabetes Medications that cause liver damage fat girls com or steatosis. Women who are pregnant or lactating. Location and Contact Information Please refer to this study by ClinicalTrials.gov identifier NCT00262964 Jennifer McCrea, MS 314-362-2846 jmccrea@wuslt.eduMaureen |
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| VLDL kinetics; 2. Insulin sensitivity in adipose tissue, liver and skeletal muscle; 3. Hepatic fat content; 4. Hepatic, subcutaneous fat, and intraabdominal fat cytokine production; 5. Arterial, portal venous, and peripheral blood cytokines. Expected Total Enrollment: 40 Study start: December 2003; Expected completion: December 2011Last follow-up: December 2008; Data entry closure: December 2008 Obesity is a major risk factor for non-alcoholic fatty liver disease (NAFLD), which represents a spectrum of liver omega3 fatty acid diseases. NAFLD is a major health problem in the US because of its high prevalence and causal relationship with serious liver abnormalities. However, the omega3 fatty acid mechanism(s)responsible for developing NAFLD omega3 fatty acid in obese persons and the effects on liver function are not known. This gap in knowledge has made it difficult to identify effective therapy. The results from these studies will lay the groundwork for the development of novel therapeutic interventions for NAFLD in obese patients. |
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