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Treatment spproaches using vitamin E, magnesium, and betaine - Fatty Liver Alternative Medicine intron a Review, August, 2002 by Lyn Patrick Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. Continued from page 2. Environmental toxins, specifically petrochemicals intron a and organic solvents, have been shown to cause NASH. (5) Specific petrochemicals implicated in one study included intron a benzene, toluene, styrene, hexane, carbon tetrachloride, chloroform, methanol, and vinyl chloride. (53) The solvents these workers were exposed to are primarily metabolized by CYP2E1, one of the two main cytochrome P450 enzymes up-regulated in the pathology of NASH. These solvents are commonly found in cigarette smoke, paints, automobile exhaust, pesticides, air fresheners, and solvents used for cleaning and dry cleaning. NASH has also been seen in individuals following intestinal surgeries, prolonged total parenteral nutrition, small intestinal diverticulosis with bacterial overgrowth, (14) protein-calorie malnutrition (kwashiorkor), starvation (anorexia nervosa), rapid weight loss, inflammatory bowel disease, and HIV infection.
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