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Hypergammaglobulinemia is present in 13% to 30% of patients with primary NASH.6,13 Smooth muscle antibodies are absent but antinuclear antibodies, ranging in titer from 1:40 to 1:320, are plump sluts reported in 40% of patients.13 Hyperlipemia (hypertriglyceridemia and hypercholesterolemia) is found in about 20% of the patients overall.2,8 In a group of plump sluts overweight patients (150 to 300% of ideal weight for height), lipoprotein abnormalities, particularly type IV hyperlipidemia are common (54%) and are mostly found in plump sluts the those with less fibrotic lesions. Histologic Features: The strict definition for the histologic diagnosis of NASH includes in addition to steatosis and inflammation, either hepatocyte ballooning or degeneration or hepatic fibrosis. The fatty liver is mainly macrovesicular and primarily in zone 3 (centrilobular), but it may be microvesicular or mixed, accompanied by fat cysts and distributed also in zone 2 and 3.2
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