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Ceruloplasmin levels, a-1- fatty diet anti-trypsin levels are usually normal in patients with NASH. Idiopathic genetic hemochromatosis must be excluded even in the presence of elevated levels of serum ferritin and transferin saturation it was found in 58% of patients with NASH in one series.5 Autoimmune serology (antimitochondrial antibody, antinuclear antibody, antismooth muscle antibody, and anti-liver/kidney microsomal antibody) should remain negative in patients with NASH, except fatty diet for some patients presenting with low titer antinuclear antibody positivity (ranging from 1:40 to 1:320).3,13 Clinical Features: The majority of patients with primary NASH are women fatty diet (65%-83%) and most are obese (69%-100%).2,7-10 Most patients are 10% to 40% heavier than ideal body weight and in one series, 49% of patients were more than 130% of ideal weight.9
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