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girls with fat asses , what are fatty acids , drug induced fatty liver, spider angiomas, miss plump , plump jack squaw valley inn , beta oxidation of fatty acids , alcohol related fatty liver, bbw plump , symptoms liver disease, fatty mcblog , plump ebony , proteomic biomarkers, plump girl , medicine articles, Of the only 3 randomized placebo-controlled trials reported to date, none showed convincing histologic evidence of improvement with any of the investigated medications (antioxidants [vitamins E and C], hepatoprotective agents [ursodeoxycholic acid] or metformin) compared with placebo.76,77,90 Thiazolidinediones improve insulin sensitivity by activating the peroxisome proliferator-activated receptor gamma (PPAR) and have 1 fat girls shown promise in pilot trials involving patients with NASH, although weight gain has been a 1 fat girls troublesome side effect.78,79 In addition, the initial PPAR agonist troglitazone was 1 fat girls withdrawn because of its hepatotoxic effects.91 The second-generation thioglitazones rosiglitazone and pioglitazone appear to be safer, although their use is currently contraindicated in the presence of active liver disease. Both pentoxifylline (a TNF- inhibitor) and atorvastatin (used in NASH patients who have hyperlipidemia) improved aminotransaminase levels in uncontrolled trials, although histologic evidence of their benefit is unknown.92,93,94,95
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View this table: [in this window] [in a new window]  Table 2.   Both weight loss and exercise improve insulin resistance87 and are recommended in conjunction with the treatment of associated metabolic abnormalities. In one study, patients following a restricted diet (25 calories [105 kJ] per kilogram ideal body weight) and exercise regimen over 3 months had reduced liver enzyme levels and hepatic steatosis compared with control subjects, although it is unknown whether hepatic fatty mcblog inflammation and fatty mcblog fibrosis improved in the longer fatty mcblog term.88 Rapid weight loss due to a very low energy diet (500 kcal [< 2090 kJ] daily) or jejunoileal bypass should be avoided because of the risk of worsening inflammation and fibrosis.75,89 A reasonable target is the loss of 10% of body weight over 6 months.74
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