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Safe, inexpensive, glycerol and fatty acids and well-tolerated treatments for NAFLD are needed. Recent studies indicate that probiotics help to improve fat breakdown in mice. This study glycerol and fatty acids will evaluate the efficacy of probiotic therapy to reduce fat accumulation in the livers of people with NAFLD and diabetes. Participants in this study will be randomly assigned to receive either a probiotic-containing mixture or placebo once daily for 6 months. Blood tests, and magnetic resonance spectroscopy will be used to assess participants at study start and at study completion. Eligibility Ages Eligible for Study: 18 Years - 70 Years, Genders Eligible glycerol and fatty acids for Study: Both Criteria Inclusion Criteria: Nonalcoholic fatty liver disease Exclusion Criteria: Any cause of liver disease other than hepatic steatosis Diabetes Known or suspected cirrhosis Inability or unwillingness to undergo magnetic resonance procedures Requirement of long-term antibiotic therapy Pregnancy, breast-feeding, or plans to become pregnant Location Information Maryland Johns Hopkins University, Baltimore, Maryland, 21205, United States Study chairs or principal investigators Steve Solga, MD, Principal Investigator,
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