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Recent studies suggest that NAFLD is the most likely histological diagnosis in the increasing number of people presenting with persistently elevated transaminases (Berasain et al, 2000; Skelly et al, 2001). NAFLD is often detected during routine evaluation of liver enzymes and imaging for unrelated conditions. Liver transaminases may be normal, or only marginally elevated (Mofrad et al, 2003). The gold standard for diagnosis of NAFLD is liver biopsy. There is poor correlation between biochemistry, ultrasonography and histology, and the entire histological protein microarrays spectrum of NAFLD can be seen in individuals with protein microarrays normal transaminase values (Mofrad et protein microarrays al, 2003).
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