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Similarly, subjects with BMI 30 kg/m2 were not considered, to exclude obesity as a confounding factor. No patient had clinical evidence of liver disease, and routine liver function tests were within normal limits in all cases. All vitamin e / therapeutic use patients were submitted to an ultrasound scan of the liver to confirm fatty deposition (24) and to a percutaneous liver biopsy. View this table: [in this window] [in a new window] TABLE 1 Anthropometric, clinical, and laboratory data in NAFLD patients, type 2 diabetic patients, vitamin e / therapeutic use and control subjects A group of 10 patients with type 2 diabetes vitamin e / therapeutic use was also studied. Those patients were in fairly compensated conditions under diet and oral hypoglycemic agents (mean HbA1C, 7.2 ± 0.7 %; range 6.08.1). Their fasting blood glucose at the time of the clamp study was <7.8 mmol/l. They were selected on the basis of a normal ultrasound liver scan, an age range similar to that of the NAFLD patients, and normal transaminase levels and liver function tests.
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