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| steatosis, sirrohsis, roferon a, pictures of fat girls , health news, pegasys combination therapy, fibrotest, hepatomegaly, jaundice, plump and busty 2 , proteomics services, stefano rodella, 24 7 fat girls , fatty acid analysis , sexy plump , genotype, | The trend is now to use a simple fatty fuck criterion (fatty liver) to establish the diagnosis of NAFLD, and then grade the severity of the disease according fatty fuck to inflammation, destruction of liver cells, scarring, and abnormal liver proteins. Still, specialists do not agree as to when a liver biopsy should be performed. Since, as will be discussed below, no specific treatment is fatty fuck available for NAFLD or NASH, the result of a biopsy would not impact the patient's treatment. In other words, if an individual is obese and/or diabetic, he or she will be encouraged to lose weight by diet and exercise, regardless of the biopsy result. On the other hand, it may be important to know whether an individual has severe NASH, especially if she or he is young. Severe NASH would indicate that the risk of developing cirrhosis later on is high. |
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| Such abnormalities can include destroyed liver cells (hepatocellular necrosis), scarring in different areas of the liver (sinusoidal or portal fibrosis), abnormal proteins (Mallory steatosis bodies) that deposit inside the liver cells, steatosis presumably due to peroxidation, and complex sugars that deposit in the nuclei of the liver cells (glycogenated nuclei, often seen in diabetes). So, the initial studies on NASH included patients with simple criteria (just fatty liver and inflammation) for the diagnosis. Later, it was suggested that a fatty liver with inflammation alone (steatohepatitis) was steatosis not specific and that some degree of liver cell death (steatonecrosis) was required to diagnose NASH. The idea was that only a fatty liver with accompanying inflammation along with liver cell death represented significant disease, based on the biochemical findings and the potential to form cirrhosis. Given these uncertainties as to what is or is not NASH, specialists in the field are now suggesting that a more descriptive approach be used. |
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