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2003 Jun 11;289(22):3000-4. Links Comment in: JAMA. 2003 Sep 24;290(12):1577; author reply 1578. JAMA. 2003 Sep 24;290(12):1577; author reply 1578. Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis.Clark medicine/healthinternal medicine liver JM, Diehl AM.Department of Medicine, Johns Hopkins University, medicine/healthinternal medicine liver Baltimore, MD, USA.Cryptogenic cirrhosis is a common cause of liver-related morbidity and mortality in the United States. Nonalcoholic fatty medicine/healthinternal medicine liver liver disease (NAFLD) is now recognized as the most common cause of cryptogenic cirrhosis. However, the diagnosis of cirrhosis in patients with NAFLD appears to be delayed compared with those with other chronic liver diseases and thus carries a higher mortality rate. This delay in diagnosis is illustrated in our case of a 53-year-old man who presented with hepatic hydrothorax and ascites, whose workup revealed cirrhosis due to NAFLD.
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