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Treatment approaches that address these etiologies are reviewed: betaine, magnesium, fat black girls and vitamin E. (Altern Med Rev 2002;7(4):276-291) Introduction Nonalcoholic fat black girls steatotic hepatitis (NASH) is part of the spectrum of nonalcoholic fatty liver disease (NAFLD), a condition becoming increasingly recognized both in the United States and worldwide due to its prevalence in obesity, diabetes, and insulin resistance syndrome. (1) NAFLD can manifest as simple steatosis (fatty liver), fat black girls which rarely has any sequelae, or can progress to steatosis with inflammation or fibrosis, in which case it is termed NASH. NASH is the most prevalent form of progressive liver disease in the United States. (2) Due to the fact that approximately 50 percent of NASH patients develop liver fibrosis--15-30 percent develop cirrhosis, and three percent may progress to liver failure (3,4)--there is an increasing need to recognize and understand the etiology and treatment of this condition.
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