Although NASH is most fatty streak plump lip

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plump lip , tests, dosing, symptoms, plump mature , treatments for nonalcoholic fatty liver diseasee, fatty ass , fatty acid definition , hep c, n 3 polyunsaturated fatty acids , combo, maldi, encephalopathy, hepatitis a, copegus, hcv drug, hcv medication, liver, plump dj , AD - Beth Israel Deaconess Medical Center, Boston, Massachusetts, fatty streak USA. PMID- 9005748 10TI - Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. AU - Sanyal AJ; Campbell-Sargent C; Mirshahi F; Rizzo WB; Contos MJ; Sterling RK; Luketic VA; Shiffman ML; Clore JN SO - Gastroenterology 2001 Apr;120(5):1183-92. BACKGROUND AND AIMS: The pathogenesis of nonalcoholic steatohepatitis (NASH) is unknown. We tested fatty streak the fatty streak hypothesis that NASH is associated with 2 defects: (1) peripheral insulin resistance, which increases lipolysis, delivery of free fatty acids (FFA) to the liver, and hepatic fatty acid beta oxidation, thereby creating oxidative stress; and (2) an abnormality within the hepatocytes that might render them more susceptible to injury from oxidative stress.
Although NASH is most often a benign disease with an indolent course, patients with this condition occasionally develop cirrhosis, portal hypertension, and hepatic failure. In some cases, NASH may be reversed with weight reduction. CONCLUSION: Nonalcoholic steatohepatitis is an important differential diagnosis for asymptomatic patients with chronically elevated plasma liver enzyme levels, especially if obesity, diabetes, or hyperlipidemia are present. Analysis of liver biopsy specimens is plump lip necessary for diagnosis and plump lip must be done in all patients with unexplained abnormal liver function and negative results on a noninvasive workup. Prognosis is good in most patients. The precise role of weight reduction and ursodeoxycholic acid therapy in the favorable alteration of the natural history of this disorder needs to be addressed in large, well-controlled studies.
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