By UTR PCR which pegasys copegasus
national library of medicine, liver infection, plump galleries , awards, plump mt , pegylated interferons, plump thighs , copegasus, hepatitis c treatments, drugs, crystallography, reference, These results suggest that certain TTV genotypes including genotype 1 pegasys influence the necrosis and inflammation of hepatocytes and liver fibrosis in NAFLD patients.PMID: 11251303 pegasys [PubMed - as supplied by publisher]  Display  Summary Brief Abstract pegasys Citation MEDLINE XML UI List LinkOut ASN.1 Related Articles Cited Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Gene (GeneRIF) Links Genome Links Project Links GENSAT Links GEO Profile Links HomoloGene Links Nucleotide Links OMIA Links OMIM (calculated) Links OMIM (cited) Links BioAssay Links Compound Links Compound via MeSH Substance Links Substance via MeSH PMC Links Cited in PMC PopSet Links Probe Links Protein Links SNP Links Structure Links UniGene Links UniSTS Links  Show  5 10 20 50 100 200 500 Sort by Pub Date First Author Last Author Journal Send to Text File Printer Clipboard E-mail Order Write to the Help Desk NCBI | NLM | NIH Department of Health & Human Services Privacy Statement | Freedom of Information Act | Disclaimer Mar 13 2006 04:32:14 bgcolor="#336699" align="left">My NCBI[Sign In] [Register] All Databases PubMed
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By UTR PCR which detects all TTV genotypes, TTV DNA was detected in 37 (97%) of the 38 patients. In contrast, N22 PCR which detects primarily TTV genotypes 1-4, detected TTV DNA in 18 patients (47%). In the liver biopsy specimens, moderate to many acidophilic bodies, moderate to marked focal/spotty necrosis of hepatocytes and marked stellate, pericellular or perivenular fibrosis were observed significantly more frequently among those who were positive for TTV DNA by N22 PCR, than among those who were copegasus negative by copegasus N22 PCR. Twelve patients (32%) were positive for TTV genotype 1. Moderate to marked copegasus vacuolation of nuclei, moderate to many acidophilic bodies, and moderate to marked focal/spotty necrosis as well as marked stellate, pericellular or perivenular fibrosis were found significantly more frequently in the TTV genotype 1-positive group than in the TTV genotype 1-negative group.
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