|
national library of medicine, liver infection, plump galleries , awards, plump mt , pegylated interferons, plump thighs , copegasus, hepatitis c treatments, drugs, crystallography, reference,
|
Reduction in weight during this period ranged from 12% to 42%.27 In contrast, the heroin weight loss induced by jejunoileal (J-I) bypass operations, in most cases, seems to be accompanied by a further increase in liver steatosis and fibrosis.28 Antibiotics After jejunoileal bypass, steatohepatitis heroin has resolved with heroin metronidazole therapy,29 but this treatment has not been evaluated in primary NASH. Ursodeoxycholic Acid (UDCA) UDCA may have a membrane - stabilizing and cytoprotective effect. Treatment of NASH with UDCA for 12 months in a pilot study resulted in significant improvements in alkaline phosphatase, alanine transaminase (ALT), g-glutamyl transpeptidase (GGT) and hepatic steatosis, although there was no significant change in mean weight.30 Clofibrate therapy for one year in patients with NASH and hypertriglyceridemia was not found to be beneficial, in the same pilot study,30 despite its lipid lowering properties. The possible benefit of UDCA therapy should be further investigated in the context of a randomized, controlled trial.
|
