Losartan has been shown healthcare gold n plump

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Losartan has been shown to reduce blood markers of hepatic fibrosis, plasma transforming growth factor- b 1 (TGF- b 1), ferritin and aminotransferase levels. Pentoxifylline is a methylxanthine compound inhibiting the production of cytokines (mainly TNF- a and TGF- b involved in the pathogenesis of NASH. Adams et al, gold n plump tested the effectiveness of this drug in NASH patients, gold n plump but its side effect (nausea, gastrointestinal discomfort in 60% of cases) did not support its use at current disorder with only a modest biochemical advantage. Liver transplantaion may be required if gold n plump cirrhosis develops and is complicated by liver failure or hepatocellular carcinoma. However recurrence of steatosis after transplantation is common (60-100% of transplant recipients) with progression to steatohepatitis reported in 1/3 of cases.) Monitoring patients with NAFLD is difficult due to the independent fluctuation of the liver enzyme levels regardless of whether liver fibrosis worsens or improves.
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