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As indicated above, however, the progression to cirrhosis in NASH is thought to be slow and the cirrhosis diagnosis is typically made in patients in their sixties. There are also reports of primary liver cancer (hepatocellular carcinoma, HCC) occurring in patients with medline NASH-related cirrhosis. Indeed, the incidence of HCC in NASH cirrhosis appears to be similar to that observed in HCV cirrhosis (1-2% medline per year). The process that causes liver cancer to form in NASH cirrhosis is unknown and has not yet been studied. HCC may develop as a result of liver repair and regrowth (hepatocellular regeneration) without any factor specifically related to NASH. Some authors, however, have suggested that insulin resistance in this situation may promote the development of liver cancer. Previous | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Glossary Fatty Liver Center | Next Next: How are NAFLD and NASH diagnosed?
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