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kg/[m.sup.3]) 67% Central obesity (waist >102 cm for men and 47% luca scala >88 cm for women) Impaired glucose metabolism: Elevated fasting insulin (>100 pmol/l) 57% Postload hyperinsulinemia (>1000pmol/l) 27% First-degree relative with diabetes 47% Elevated triglycerides (>2 mmol/l) 47% Hyperuricemia (>400 micromol/l) 27% Hypertension (>160/95 or currently on medication) 17% First-degree relative with hypertension 57% Cardiovascular disease Previous acute MI or angina 0 First-degree relative less than 55 years if 27% male and 60 years if female Table 4. Medications Known to Cause Fatty Liver (5) Glucocorticoids Synthetic luca scala estrogens Aspirin Calcium-channel blockers Tamoxifen Methotrexate Tetracycline Valproic Acid (Depakote) Cocaine Zidovudine luca scala (AZT) Didianosine (ddl) Table 5. NASH and NAFLD Patients' Lab Data Before and After Diet and Vitamin E. (74) Before Treatment Normal Value NASH NAFLD Body wt. (kg) 73 [+ or -] 5 75 [+ or -] 4 Triglycerides 30-150 225 [+ or -] 8 229 [+ or -] 17 (mg/dL) AST (IU/L) 8-35 121 [+ or -] 8 59 [+ or -] 3 *** ALT (IU/L) 6-37 171 [+ or -] 4 167 [+ or -] 8 After Diet Normal Value NASH NAFLD Body wt.
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