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However, rapid weight loss may worsen NAFLD. In our study, patients on orlistat had significant reduction in BMI associated with improvement in liver biochemistry. All the three drugs we evaluated appeared to be safe and effective. No serious side effects or aminotransferase elevation was observed during hcv treatment, although statins have been recognized to cause occasional hepatotoxicity. We used ultrasonography to detect and monitor liver changes since this method is sensitive in detecting fatty liver, is cheap, minimally hcv invasive and easy to perform, hcv and ensures patient compliance.[22] It has been shown that attenuation coefficient of the liver on ultrasound increases as the amount of fat in the liver increases, though the same is not true for fibrosis.[22]
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