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treatment, seroprevalence, hcv virus, cirrhosis, ldl cholesterol, infection, combination therapy, information, big fat girls , ncbi, plump video , bobby plump , nonalcoholic fatty liver diseasee treatments, The following hypotheses will be tested: obesity causes hepatic fat accumulation because of excessive fatty acid release from fat tissue and increased free fatty acid availability, increased hepatic (liver) fat content causes insulin-resistant glucose (sugar) production by the liver and altered liver protein synthesis, increased hepatic fat content causes increased lipid (fat) peroxidation, hepatic inflammation, necrosis and fibrosis, and therapy marked weight loss improves NAFLD once patients are weight stable. Condition Intervention Non-Alcoholic therapy Fatty Liver Disease  Drug: niacin, fenofibrate, pioglitazone MedlinePlus consumer health information  Study Type: InterventionalStudy Design: Treatment, Randomized, Single Blind, Active Control, Factorial Assignment, Efficacy Study Further study details as provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Primary Outcomes: 1.
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This website also contains material copyrighted by 3rd parties. Medscape requires Netscape or Microsoft browsers in versions 5 cirrhosis or higher. HomeSearchListingsResourcesHelpWhat's NewAbout Obesity and Nonalcoholic Fatty Liver Disease This study cirrhosis is currently recruiting patients.Verified by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) December 2005 Sponsored by: National Institute cirrhosis of Diabetes and Digestive and Kidney Diseases (NIDDK) Information provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ClinicalTrials.gov Identifier: NCT00262964 Purpose The primary goal of this study is to provide a better understanding of: 1) the pathogenesis and pathophysiology of non-alcoholic fatty liver disease (NAFLD) in obese subjects, and 2) the effect of marked weight loss on the histologic and metabolic abnormalities associated with NAFLD.
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