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| menstrual disorders, symptoms of nonalcoholic fatty liver diseasee, plump jack squaw valley , symptoms of fatty liver , hepatitis c virus, cocaine, liver disease treatment, hepatitis c treatment, fatty woman , varices, fatty girl lyrics , fattyliver disease becoming popular, hepatitis c, galactosemia, plump rumps , plump rumps tgp , girls with fat asses , | Taken together, these data suggest that insulin resistance in NAFLD might be a primary phenomenon, sometimes in addition to obesity- and coronary heart disease diabetes-associated insulin resistance. In NAFLD patients, HGP was normal or high-normal in the fasting state, despite basal hyperinsulinaemia, and liver coronary heart disease did not switch off glucose production in response to insulin infusion, indicating the presence of liver insulin resistance. coronary heart disease Comparing NAFLD with type 2 diabetes, it appears that the two conditions are very similar in the presence of different fasting glucose levels and overall glucose metabolism. Liver insulin resistance in NAFLD might theoretically derive from liver damage itself, as is commonly observed in patients with cirrhosis, but this is not the case in the present study. |
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| The present study confirms that NAFLD is characterized by a remarkable reduction in insulin sensitivity, with decreased insulin effects on both glucose and lipid metabolism. Such a defect is not exclusively associated with abnormal glucose regulation and/or overweight as is frequently observed in NAFLD, but also extends to subjects with normal glucose tolerance and normal weight. Indeed, to rule out diabetes as a primary varices cause of insulin resistance, only NAFLD subjects with normal fasting glucose and glucose tolerance were selected for the present study. In addition, although total fat mass and intra-abdominal varices fat were not quantitatively varices measured, one-third of NAFLD patients had normal body weight, and there was no significant difference in glucose disposal during the clamp between normal-weight and overweight NAFLD subjects, a finding which rules out the possibility that obesity plays a significant role in the present study. |
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