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Perhaps the main agents available are metformin, vitamin E and urodeoxycholic acid. A few patients pegasus do progress to cirrhosis and liver pegasus failure and these should be considered for liver transplantation though recurrence of NASH after transplantation has been recorded. Back to top HIGHLIGHTS asymptomatic in most cases obesity, diabetes mellitus, hypertension and hyperlipidaemia are frequent associated features increase plasma ALT the commonest liver function test abnormality NASH accounts for most cases of isolated increased plasma transaminase activity of otherwise unknown cause liver biopsy rarely needed long-term prognosis is favourable graduated weight loss pegasus is the best available treatment Back to top References Angullo P.
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