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Insulin resistance and hyperinsulinemia have been associated with increased collagen pegasist production by hepatic stellate cells. Subjects with hepatitis C and NAFLD are more likely to be virologic nonresponders following anti-HCV therapy. The value of treating insulin resistance and NAFLD prior to antiviral therapy remains to be verified. Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Health System, Richmond, VA, USA. 10/28/05 Reference A J Sanjal. Review article: non-alcoholic fatty liver disease and hepatitis C - risk factors and clinical implications. Alimentary Pharmacology and Therapeutics 22 pegasist (Suppl 2):48-51. November 2005. pegasist See Also Biochemical Markers (Fibrotest) Reliably Predict Extensive Fibrosis and Cirrhosis in Non Alcoholic Fatty Liver Disease (NAFLD) 04/30/04 All HCV Topics [ A to Z ] 2-log Drop Acute (Primary) HCV Infection Age Alcohol / Smoking / Diabetes ALT Anemia Children Chronic HCV Infection Cirrhosis Cognitive Behavioral Therapy Complementary Therapies (CAM) Combination Treatment Cryoglobulinemia / Cryoglobulin Disease Progression Decompensation Developing Countries Depression Diabetes Mellitus Dosing Drug Abuse Drug
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