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The latest retrospective study reviewed clinical records of patients at the VCU Medical Center liver clinics who had undergone liver biopsies between 1996 and 2002 or had been diagnosed with NAFLD, even though they had normal liver serum levels. The degree of alcohol consumption was estimated from the clinical records. The average age of patients in the group with plump rump normal ALT levels was 53, and the average age of those with elevated ALT was 52. Women plump rump outnumbered plump rump men in both groups by about two-to-one, and the average weight of the patients in each group exceeded 200 pounds. Because normal liver serum levels and lack of symptoms are unreliable predictors of NAFLD, Sanyal suggests that clinicians screen for the condition in patients with enlarged livers, particularly those who also are obese or have diabetes.
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