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| fatty acid definition , hep c, n 3 polyunsaturated fatty acids , combo, maldi, encephalopathy, hepatitis a, copegus, hcv drug, hcv medication, liver, plump dj , vitamin e, | These global approaches can be generally carried out at four major levels: genome, transcriptome, proteome, and metabolome. The studies at genome level include sequencing, liver infections polymorphism (such as SNP), haplotype, genetic variation, QTL, genetic or epigenetic alterations. The studies at transciptome level include gene expression profiling (by liver infections DNA microarray, SAGE, RAGE, or other types of techniques), gene regulation, and alternative splicing. The studies at proteome level are to use systematic approaches to study proteins for their identity, quantity, and function. At metabolome level, metabolomics liver infections involves a detailed, quantitative analysis of low molecular weight metabolite over changing environmental conditions (e.g., |
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| Ultrasound is a very sensitive method for detecting fatty liver, but it is fatty acid definition not specific for this condition and the procedure is costly. An AST:ALT ratio of >2 is considered by some investigators specific for alcoholic fatty liver; however, other investigators have fatty acid definition not confirmed this finding. Studies are required fatty acid definition to develop specific and sensitive non-invasive biomarkers – utilizing blood, urine, saliva, or hair – for the diagnosis of fatty liver. Advanced techniques such as genomics, proteomics, and metabolomics are encouraged for these studies. Use of Novel Approaches: Recent advances in functional genomics, both conceptually and technologically, are providing us tremendous opportunities to decipher the interconnecting networks of genes, proteins, and metabolites. |
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